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Literature summary for 1.13.99.1 extracted from

  • Sharma, I.; Dutta, R.K.; Singh, N.K.; Kanwar, Y.S.
    High glucose-induced hypomethylation promotes binding of Sp-1 to myo-inositol oxygenase implication in the pathobiology of diabetic tubulopathy (2017), Am. J. Pathol., 187, 724-739 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.13.99.1

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
myo-inositol + O2 Homo sapiens
-
 D-glucuronate + H2O
-
 ?
myo-inositol + O2 Mus musculus
-
 D-glucuronate + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Mus musculus Q9QXN5
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HK-2 cell
-
 Homo sapiens
-
kidney
-
 Mus musculus
-
renal proximal tubule cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
myo-inositol + O2
-
 Homo sapiens D-glucuronate + H2O
-
 ?
myo-inositol + O2
-
 Mus musculus D-glucuronate + H2O
-
 ?

Synonyms

Synonyms Comment Organism
MIOX
-
 Homo sapiens
MIOX
-
 Mus musculus
Myo-inositol oxygenase
-
 Homo sapiens
Myo-inositol oxygenase
-
 Mus musculus

Expression

Organism Comment Expression
Homo sapiens under high-glucose (30 mM) ambience, the enzyme expression increases compared with the control low-glucose (5 mM) ambience up
Mus musculus under high-glucose (30 mM) ambience, the enzyme expression increases compared with the control low-glucose (5 mM) ambience up